Preheat the skillet: Heat 1-2 tablespoons avocado or olive oil in a large nonstick skillet over medium heat.
Prepare the fish: Pat dry 6 tilapia filets (4-ounces each) with paper towels. If frozen, thaw first. Season with ½ teaspoon table or sea salt and ⅛ teaspoon freshly ground black pepper.
Bread the fillets: Pour ⅔ cup dry bread crumbs onto a plate. Press both sides of each fillet into the crumbs to coat.
Sauté: Cook for 2–3 minutes per side until golden brown and nearly cooked through.
Add the toppings: Divide ½ cup pizza sauce among the fillets and sprinkle with 2 ounces shredded mozzarella cheese.
Melt the cheese: Reduce the heat to low and cover the skillet. Cook briefly, until the cheese melts and the thickest part of the fish reaches 145°F (63°C).
Garnish and serve: Sprinkle with fresh basil and serve immediately.